Cancer Research UK figures show number diagnosed with most serious form of skin cancer has risen above 20,000 for first time

The number of cases from the most serious form of skin cancer have reached a record high across the UK, according to analysis by a leading cancer charity.

Melanoma cases in the UK have risen above 20,000 for the first time ever, with 20,980 people being diagnosed with the form of cancer in 2022, according to analysis of the latest figures by Cancer Research UK.

PhenMap tool could spare thousands of patients from treatment that would be ineffective for them

A new AI-driven way of identifying how patients with advanced bowel cancer will respond to a drug that was recently introduced by the NHS has been announced.

Researchers at London’s Institute of Cancer Research and the RCSI University of Medicine and Health Sciences in Dublin have developed the method with the goal of sparing potentially thousands of patients from being given drugs that would be ineffective in fighting their cancers.

Relacorilant, typically used to treat Cushing’s syndrome, could improve outcomes in platinum-resistant cases

A drug originally used to treat a rare disease could extend the lives of patients with an aggressive form of ovarian cancer, according to a clinical trial.

Platinum-resistant ovarian cancer occurs when the disease progresses within six months of starting platinum-based chemotherapy. This form of chemotherapy is different from other types because it uses compounds that contain platinum to destroy cancer cells by preventing them from dividing.

Treatments continue to improve. The challenge now facing ministers is hugely unequal outcomes

New analysis from Cancer Research UK, revealing a 29% drop in the rate of people dying from cancer compared with 40 years ago, is a vital counterpoint to grim health headlines about the UK’s outcomes falling behind those of other countries, and the NHS missing its own cancer targets. Prof Chris Whitty, the chief medical officer for England, made a related point in a recent lecture. Stand back from the day to day, he said, and the extraordinary leaps forward enabled by vaccinations and other advances in treatment and public health come into focus.

This longer view is not a cause for complacency or inaction. England’s latest cancer plan, launched last month, highlighted shocking lapses including lengthy waits for treatment and a failure to tackle inequalities in cancer mortality dating back 15 years. Last year, analysis by the Guardian found that about three-quarters of NHS trusts were failing to reach standards relating to diagnosis and treatment.

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Largest study of its kind suggests high red meat consumption has biggest impact, followed by smoking

More than a quarter of healthy years lost to breast cancer are due to lifestyle factors such as red meat intake and smoking, according to the largest study of its kind.

The study, published in the Lancet Oncology, used data from population-based cancer registries to produce a comprehensive analysis of breast cancer and its risk factors.

Swedish study of 100,000 women found higher rate of early detection, suggesting potential to support radiologists

The use of artificial intelligence in breast cancer screening reduces the rate of a cancer diagnosis by 12% in subsequent years and leads to a higher rate of early detection, according to the first trial of its kind.

Researchers said the study was the largest to date looking at AI use in cancer screening. It involved 100,000 women in Sweden who were part of mammography screening and were randomly assigned to either AI-supported screening or to a standard reading by two radiologists between April 2021 and December 2022.

Cancer charity highlights apparent ‘postcode lottery’ of testing and diagnoses across different regions seen in study

Prostate cancer is now the most commonly diagnosed form of cancer across the UK, surpassing breast cancer, according to a leading charity.

There were 64,425 diagnoses of prostate cancer in 2022, an analysis of NHS figures by Prostate Cancer UK found, and 61,640 new cases of breast cancer.

King extols early diagnosis which can give ‘invaluable time’ and backs launch of screening checker tool

King Charles has hailed a “milestone” in his “cancer journey” and revealed he is to reduce his schedule of treatment in the new year, describing the news as a “personal blessing”.

His treatment will move into a precautionary phase with its regularity significantly reduced as his recovery reaches a very positive stage, it is understood. His medical team will assess how much longer he will require treatment to protect and prioritise his continued recovery.

New technologies can reduce our reliance on animal experiments. This isn’t just morally right, it could have scientific and economic benefits too

Science is a slaughterhouse. We rarely acknowledge the degree to which animal life underwrites the research that provides us with medicines, or the regulation that keeps us safe. Live animals were used in 2.64m officially sanctioned scientific procedures in the UK in 2024, many of them distressing or painful and many of them fatal. But the government’s new strategy to phase out animal testing – published earlier this month – suggests that in the near future emerging technologies can largely replace the use of animals in our scientific endeavours.

The UK previously banned cosmetics testing on animals, and has already taken steps to regulate and reduce their use in research. But some needlessly cruel experiments still take place: the forced swim test (FST) for example, in which a rodent is placed in a body of water it cannot escape and researchers measure whether antidepressants extend the time it struggles for life. The government says no new FST licences will be granted, in effect banning it. Similar targets are set over the next few years to end the testing of caustic chemicals on eyes and skin.